Oxygen radicals, inflammation, and arthritis: Pathophysiological considerations and implications for treatment
References (173)
Biological effects of the superoxide radical
Arch Biochem Biophys
(1986)- et al.
New perspectives on the biochemistry of superoxide anion and the efficiency of superoxide dismutases
Biochem Pharmacol
(1990) - et al.
Superoxide dismutase: an enzymic function for erythrocuprein (hemocuprein)
J Biol Chem
(1969) The superoxide forming enzymatic system of phagocytes
Free Radicals Biol Med
(1988)- et al.
Mechanism of exacerbation of rheumatoid synovitis by total-dose iron dextran infusion: In vivo demonstration of iron promoted oxidant stress
Lancet
(1987) - et al.
The catalytic activity of iron in synovial fluid as monitored by the ascorbate free radical
Free Radical Biol Med
(1990) - et al.
Superoxide and hydrogen peroxide production by macrophages of New Zealand black mice
Free Radicals Biol Med
(1990) - et al.
Serum factors from patients with systemic lupus erythematosus enhancing superoxide generation by normal neutrophils
J Invest Dermatol
(1983) - et al.
The presence of hyaluronidase in various mammalian tissues
J Biol Chem
(1963) - et al.
The reactivity of various free radicals with hyaluronic acid: Steady state and pulse radiolysis studies
Biochim Biophys Acta
(1987)
The role of superoxide and hydroxyl radicals in the degradation of hyaluronic acid induced by metal ions and by ascorbic acid
J Inorganic Biochem
Role of singlet oxygen in the degradation of hyaluronic acid
Biochem Biophys Res Commun
Chemical changes involved in the oxidative reductive depolymerization of hyaluronic acid
J Biol Chem
Nonenzymatic degradation of acid-soluble calf skin collagen by superoxide ion: Protective effect of flavonoids
Biochem Pharmacol
Collagen degradation by superoxide anion in pulse and gamma radiolysis
Biochem Biophys Acta
Degradation of soluble collagen by ozone or hydroxyl radicals
FEBS Lett
The effect of oxidants on neutrophil mediated degradation of glomerular basement membrane collagen
Biochim Biophys Acta
A novel mechanism for oxidative cleavage of prolyl peptides induced by the hydroxyl radical
Biochem Biophys Res Commun
Evidence for free radical involvement in the hydroxylation of proline: inhibition by nitroblue tetrazolium
FEBS Lett
Involvement of superoxide in the prolyl and lysyl hydroxylase reactions
Biochem Biophys Res Commun
Involvement of superoxide in the paraquat induced enhancement of lung collagen synthesis in organ culture
Biochem Biophys Res Commun
Chemical effects of UV radiation on aqueous solutions of chondroitin sulfate
Polymer Photochem
Suppression of human lymphocyte proliferation by activated neutrophils or H2O2: surviving cells have an altered T helper/T suppressor ratio and an increased resistance to secondary oxidant exposure
Clin Immunol Immunopathol
Inhibition of proteoglycan synthesis by hydrogen peroxide in cultured bovine articular cartilage
Biochim Biophys Acta
Hyaluronic acid synthesis in articular cartilage: an inhibition by hydrogen peroxide
Biochem Biophys Res Commun
Collagenolytic metalloenzymes of the human neutrophil
Biochem Pharmacol
Superoxide dependent oxidation of extracellular reducing agents by isolated neutrophils
J Biol Chem
Free radicals and tissue injury
Lab Invest
Oxygen toxicity, oxygen radicals, transition metals, and disease
Biochem J
The sensitization of the toxicity of superoxide and vitamin C by copper and iron: A site specific mechanism
Biological defense mechanisms: The production by leukocytes of superoxide, a potential bactericidal agent
J Clin Invest
Phagocytes, O2 reduction, and hydroxyl radical
Rev Infect Dis
Oxygen derived free radicals in post ischemic tissue injury
N Engl J Med
Reperfusion and reperfusion injury
Clin Res
Hypoxic reperfusion injury in the inflamed human joint
Lancet
Is chronic synovitis an example of reperfusion injury?
Ann Rheum Dis
Oxygen free radicals, inflammation, and synovitis: The current status
Ann Rheum Dis
Hypoxia and acidosis in chronic inflammatory arthritis: relation to vascular supply and dynamic effusion pressure
J Rheumatol
The effect of synovial iron on the progression of rheumatoid disease: A histologic assessment of patients with early rheumatoid synovitis
Arthritis Rheum
Bleomycin detectable iron in kneejoint synovial fluid from arthritic patients and its relationship to the extracellular oxidant activities of ceruloplasmin, transferrin, and lactoferrin
Biochem J
Lipid peroxidation in rheumatoid arthritis: Thiobarbituric acid reactive material and catalytic iron salts in synovial fluid from rheumatoid patients
Clin Sci
Intraarticular ferritin bound iron in rheumatoid arthritis
Arthritis Rheum
Monocyte superoxide anion production in rheumatoid arthritis: Preliminary evidence for enhanced rates of superoxide production by monocytes from patients receiving penicillamine, sodium aurothiomalate, and corticosteroids
Ann Rheum Dis
Untersuchungen zur Sauerstoffradikalfreisetzung aus peripheren humanen Phagozyten (Granulozyten und Monozyten) bei Patienten mit Chronisher Polyarthritis
Zeitschrift fur Rheumatologie
Superoxide anion production by circulating polymorphonuclear leucocytes in rheumatoid arthritis
Clin Rheum
Depressed superoxide radical generation by neutrophils from patients with rheumatoid arthritis and neutropenia: Correlation with neutrophil reactive IgG
Ann Rheum Dis
Auto-oxidative damage in Behcet's disease—Endothelial cell damage following the elevated oxygen radicals generated by stimulated neutrophils
Clin Exp Immunol
Free radicals and inflammation: Protection of synovial fluid by superoxide dismutase
Science
Degradation of hyaluronic acid by polymorphonuclear leukocytes
Inflammation
Cited by (168)
Synergy between cyclooxygenase-2 inhibitors and hyaluronic acid in the treatment of osteoarthritis: Illumination of signaling cascade, nanotechnology-driven delivery strategies and future prospects
2024, Journal of Drug Delivery Science and TechnologyCombination of curcumin and catalase protects against chondrocyte injury and knee osteoarthritis progression by suppressing oxidative stress
2023, Biomedicine and PharmacotherapyEvaluation of thiol/disulfide homeostasis in rheumatoid arthritis and disease activity
2023, Clinical BiochemistryCitation Excerpt :Disruption of the balance between free radical production and scavenging has been shown to be closely related to many pathological conditions in biological systems. It has been reported that the role of other inflammatory cells, including granulocytes, in the development of joint damage, and especially in cartilage degeneration, is a critical factor in supporting oxidative stress through the production of ROS and the release of lysosomal enzymes that increase inflammation [9–11]. The human body has a variety of enzymatic and non-enzymatic antioxidant defense molecules, including thiols.
Manganese dioxide nanoparticles protect cartilage from inflammation-induced oxidative stress
2019, BiomaterialsCitation Excerpt :To overcome bioavailability and stability issues, direct intra-injection of antioxidants such as Vitamin C [15] and polyphenols like resveratrol [16–18] or combination treatments of epigallocatechin gallate and tannic acid [19] have been explored. However, even with intra-articular injections, small molecules are rapidly cleared from the joint within hours via synovial vasculature and larger macromolecules within days via synovial lymphatics [20–22]. As a result, high doses and/or frequent injections are required to observe therapeutic benefits [23].
The intricate role of selenium and selenoproteins in erythropoiesis
2018, Free Radical Biology and Medicine
- 1
From the Division of Rheumatology, Long Island Jewish Medical Center, New Hyde Park, NY.