Seminars in Arthritis and Rheumatism
Volume 39, Issue 6 , Pages 515-520 , June 2010

Kikuchi Fujimoto Disease in Israel—More Than a Pain in the Neck

  • Doron Rimar, MD

      Affiliations

    • The Ruth and Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel
    • Department of Medicine, Carmel Medical Center, Haifa, Israel
    • Corresponding Author InformationAddress reprint requests to: Doron Rimar, MD, Dept. of Medicine, Carmel Medical Center, 7 Michal Street, Haifa 34362, Israel
    • ,
  • Devy Zisman, MD

      Affiliations

    • The Ruth and Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel
    • Department of Medicine, Carmel Medical Center, Haifa, Israel
    • ,
  • Yaakov Schendler, MD

      Affiliations

    • The Ruth and Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel
    • Department of Pathology, Carmel Medical Center, Haifa, Israel
    • ,
  • Daniel Benharroch, MD

      Affiliations

    • Department of Pathology, Soroka Medical Center, Ben Gurion University, Beer Sheva, Israel
    • ,
  • Oleg Kharenko, MD

      Affiliations

    • Department of Pathology, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    • ,
  • Alexander Brodsky, MD

      Affiliations

    • The Ruth and Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel
    • Department of Pathology, Bnai-Zion Medical Center, Haifa, Israel
    • ,
  • Marina Okopnik, MD

      Affiliations

    • The Ruth and Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel
    • Department of Pathology, Rambam Medical Center, Haifa, Israel
    • ,
  • H. Bitterman, MD

      Affiliations

    • The Ruth and Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel
    • Department of Medicine, Carmel Medical Center, Haifa, Israel

References 

  1. Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytes: a clinicopathological study. Acta Hematol Jpn. 1972;35:379–380
  2. Fujimoto Y, Kozima Y, Yamaguchi K. Cervical subacute necrotizing lymphadenitis: a new clinicopathologic entity. Naika. 1972;20:920–927
  3. Bosch X, Guilabert A, Miquel R, Campo E. Enigmatic Kikuchi-Fujimoto disease: a comprehensive review. Am J Clin Pathol. 2004;122:141–152
  4. Lin HC, Su CY, Huang CC, Hwang CF, Chien CY. Kikuchi's disease (A review and analysis of 61 cases). Otoralyngol Head Neck Surg. 2003;128:650–653
  5. Kuo T. Kikuchi's disease (histiocytic necrotizing lymphadenitis) (A clinicopathologic study of 79 cases with an analysis of histologic subtypes, immunohistology, and DNA ploidy). Am J Surg Pathol. 1995;19:798–809
  6. Tsang WYW, Chan JKC, Ng CS. Kikuchi's lymphadenitis (A morphologic analysis of 75 cases with special reference to unusual features). Am J Surg Pathol. 1994;18:219–231
  7. Kikuchi M, Takeshita M, Eimoto T. Histiocytic necrotizing lymphadenitis: clinicopathologic, immunologic, and HLA typing study. In:  Hanaoka M,  Kadin ME,  Mikata A, et al. editor. Lymphoid malignancy: immunocytology and cytogenetics. New York (NY): Field and Wood Medical; 1990;p. 51–257
  8. Yu HL, Lee SS, Tsai HC, Huang CK, Chen YS, Lin HH, et al. Clinical manifestations of Kikuchi's disease in southern Taiwan. J Microbiol Immunol Infect. 2005;38(1):35–40
  9. Pileri AS, Pileri A, Yasukawa K, Kuo TS, Sullivan K. The karma of Kiluchi's disease. Clin Immunol. 2005;114:27–29
  10. Dorfman RF. Histiocytic necrotizing lymphadenitis of Kikuchi and Fujimoto. Arch Pathol Lab Med. 1987;111:1026–1029
  11. Gross M, Maly B, Arevalo C, Eliashar R. Acute otitis media and subdural abscess as primary manifestations of Kikuchi's disease. Otolaryngol Head Neck Surg. 2004;130(3):391–394
  12. Heldenberg D, Amar M, Ben-Arie Y, Iuchtman M. Axillary involvement in pediatric Kikuchi's disease. Eur J Pediatr Surg. 1996;6(1):32–34
  13. Rudniki C, Kessler E, Zarfati M, Turani H, Bar-Ziv Y, Zahavi I. Kikuchi's necrotizing lymphadenitis: a cause of fever of unknown origin and splenomegaly. Acta Haematol. 1988;79(2):99–102
  14. Liel Y, Gaspar N, Sobel RR, Goldstein J. [Histiocytic necrotizing lymphadenitis of Kikuchi and Fujimoto]. Harefuah. 1991;120(1):15–17[Hebrew]
  15. Somech R, Leider-Trejo L, Assia A, Jurgenson U, Spirer Z. Kikuchi Fujimoto disease: a rare presentation in a child and an updated review of the literature. Acta Paediatr. 1402;91(12):1402
  16. Laufer L, Schulman H, Barki Y, Gatot A, Fliss DM. CT and US features of cervical lymphadenopathy due to Kikuchi's disease. Indian J Otolaryngol Head Neck Surg. 1997;49(4):337–340
  17. Krause I, Yankevich A, Fraser A, Rosner I, Mader R, Zisman D, et al. Behcet disease in adult Druzes in north Israel: the influence of ethnic origin on disease expression and severity. J Clin Rheumatol. 2007;13(3):124–127
  18. Westney GE, Judson MA. Racial and ethnic disparities in sarcoidosis: from genetics to socioeconomics. Clin Chest Med. 2006;27(3):453–462vi

 No funding support was received.

 The authors have conflicts of interest to disclose.

PII: S0049-0172(09)00033-X

doi: 10.1016/j.semarthrit.2009.03.003

Seminars in Arthritis and Rheumatism
Volume 39, Issue 6 , Pages 515-520 , June 2010

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