Seminars in Arthritis and Rheumatism
Volume 40, Issue 3 , Pages 222-232 , December 2010

A Randomized Trial of Three Psychosocial Treatments for the Symptoms of Rheumatoid Arthritis

  • Arthur J. Barsky, MD

      Affiliations

    • Department of Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
    • Corresponding Author InformationAddress reprint requests to Arthur J. Barsky, MD, Department of Psychiatry, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115
    • ,
  • David K. Ahern, PhD

      Affiliations

    • Department of Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
    • ,
  • E. John Orav, PhD

      Affiliations

    • Division of General Internal Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
    • ,
  • Yvonne Nestoriuc, PhD

      Affiliations

    • Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
    • ,
  • Matthew H. Liang, MD, MPH

      Affiliations

    • Department of Clinical Psychology and Psychotherapy, Philipps University of Marburg, Marburg, Germany
    • ,
  • Ilana T. Berman, PhD, MA

      Affiliations

    • The University of North Carolina at Chapel, NC
    • ,
  • Joshua R. Kingsbury, MS

      Affiliations

    • University of Illinois at Urbana-Champagne, IL
    • ,
  • Jennifer T. Sy, MS

      Affiliations

    • University of Wyoming, Laramie, WY
    • ,
  • Kathryn G. Wilk, CPNP, MS, NP

      Affiliations

    • The MGH Institute of Health Professions Graduate Nursing Program, Boston, MA

References 

  1. Papageorgiou AC, Badley EM. The quality of pain in arthritis: the words patients use to describe overall pain and pain in individual joints at rest and on movement. J Rheumatol. 1989;16:106–112
  2. Charter RA, Nehemkis AM, Keenan MA, Person D, Prete PE. The nature of arthritic pain. Br J Rheumatol. 1985;24:53–60
  3. Moldofsky H, Chester WJ. Pain and mood patterns in patients with rheumatoid arthritis: a prospective study. Psychosom Med. 1970;32:309–318
  4. Flor H, Turk DC. Chronic back pain and rheumatoid arthritis: predicting pain and disability from cognitive variables. J Behav Med. 1988;11:251–265
  5. Hagglund KJ, Haley WE, Reveille JD, Alarcon GS. Predicting individual differences in pain and functional impairment among patients with rheumatoid arthritis. Arthritis Rheum. 1989;32:851–858
  6. DeVellis R, DeVellis B, Sauter S, Harring K, Cohen J. Predictors of pain and functioning in arthritis. Health Educ Res. 1986;1:61–67
  7. Callahan LF, Brooks RH, Summey JA, Pincus T. Quantitative pain assessment for routine care of rheumatoid arthritis patients, using a pain scale based on activities of daily living and a visual analog pain scale. Arthritis Rheum. 1987;30:630–636
  8. Dwosh IL, Giles AR, Ford PM, Pater JL, Anastassiades TP. Plasmapheresis therapy in rheumatoid arthritis. New Engl J Med. 1983;308:1124–1129
  9. Zautra AJ, Davis MC, Reich JW, Nicassio P, Tennen H, Finan P, et al. Comparison of cognitive behavioral and mindfulness meditation interventions on adaptation to rheumatoid arthritis for patients with and without history of recurrent depression. J Consult Clin Psychol. 2008;76:408–421
  10. Dixon KE, Keefe FJ, Scipio CD, Perri LM, Abernethy AP. Psychological interventions for arthritis pain management in adults: a meta-analysis. Health Psychol. 2007;26:241–250
  11. Astin JA, Beckner W, Soeken K, Hochberg MC, Berman B. Psychological interventions for rheumatoid arthritis: A meta-analysis of randomized controlled trials. Arthr & Rheum. 2002;47:291–302
  12. Superio-Cabuslay E, Ward M, Lorig K. Patient education interventions in osteoarthritis and rheumatoid arthritis: a meta-analytic comparison with nonsteroidal antiinflammatory drug treatment. Arthritis Care Res. 1996;9:292–301
  13. Bradley LA, Young LD, Anderson KO, Turner RA, Agudelo CA, McDaniel LK, et al. Effects of psychological therapy on pain behavior of rheumatoid arthritis patients: treatment outcome and six-month follow up. Arthritis Rheum. 1987;30:1105–1114
  14. Bradley LA, Alberts KR. Psychological and behavioral approaches to pain management for patients with rheumatic disease. Rheum Dis Clin North Am. 1999;25:215–232
  15. Bradley LA, Young LD, Anderson KO, Turner RA, Agudelo CA, McDaniel LK, et al. Effects of cognitive-behavioral therapy on rheumatoid arthritis pain behavior: one-year follow-up. In:  Dubner R,  Gebhart GF,  Bond MR editor. Proceedings of the Vth World Congress on Pain. New York (NY): Elsevier Science; 1988;p. 310–314
  16. NIH Technology Assessment Panel on Integration of Behavioral and Relaxation Approaches Into the Treatment of Chronic Pain and Insomnia. Integration of behavioral and relaxation approaches into the treatment of chronic pain and insomnia. JAMA. 1996;276:313–318
  17. Vickers A, Zollman C. Hypnosis and relaxation therapies. BMJ. 1999;319:1346–1349
  18. Dusek JA, Otu HH, Wohlhueter AL, Bhasin M, Zerbini LF, Joseph MG, et al. Genomic counter-stress changes induced by the relaxation response. PLoS One. 2008;3:e2576
  19. Jacobsen E. Progressive Relaxation. 2nd ed.. Chicago (IL): University Press; 1938;
  20. Lundgren S, Stenström CH. Muscle relaxation training and quality of life in rheumatoid arthritis. Scand J Rheumatol. 1999;28:47–53
  21. Scott J, Huskisson EC. Accuracy of subjective measurements made with or without previous scores—an important source of error in serial measurement of subjective states. Ann Rheum Dis. 1979;39:558–559
  22. Huskisson EC. Measurement of pain. Lancet. 1974;2:1127–1131
  23. Huskisson EC. Visual Analog Scales. In:  Melzack R editors. Pain Measurement and Assessment. New York (NY): Raven Press; 1983;p. 33–37
  24. Meenan RF, Mason JH, Anderson JJ, Guccione AA, Kazis LE. AIMS2 (The content and properties of a revised and expanded arthritis impact measurement scales health status questionnaire). Arthritis Rheum. 1992;35:1–10
  25. Meenan RF, Gertman PM, Mason JR, Dunaif R. The Arthritis Impact Measurement Scales: further investigations of a health status measure. Arthritis Rheum. 1982;25:1048–1053
  26. Anderson JJ, Firschein HE, Meenan RF. Sensitivity of a health status measure to short-term clinical changes in arthritis. Arthritis Rheum. 1989;32:844–850
  27. Meenan RF, Gertman PM, Mason JH. Measuring health status in arthritis: the Arthritis Impact Measurement Scales. Arthritis Rheum. 1980;23:146–152
  28. Wolfe F. The prognosis of rheumatoid arthritis: assessment of disease activity and disease severity in the clinic. Am J Med. 1997;103:12S–18S
  29. Stucki G, Liang MH, Stucki S, Bruhlmann P, Michel BA. A self-administered rheumatoid arthritis disease activity index (RADAI) for epidemiological research. Arthritis Rheum. 1995;38:795–798
  30. Ward M. Relative sensitivity to change of the erythrocyte sedimentation rate and serum C-reactive protein concentration in rheumatoid arthritis. J Rheumatol. 2003;31:884–895
  31. van der Heijde DM, van't Hof MA, van Riel PL. Validity of single variables and composite indices for measuring disease activity in rheumatoid arthritis. Ann Rheum Dis. 1992;51:177–181
  32. Fuchs HA, Pincus T. Reduced joint counts in controlled clinical trials in rheumatoid arthritis. Arthritis Rheum. 1994;37:470–475
  33. Prevoo MLL, van't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LBA, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Arthritis Rheum. 1995;38:44–48
  34. Smolen JS, Breedveld FC, Eberl G, Jones I, Leeming M, Wylie GL, et al. Validity and reliability of the twenty-eight-joint count for the assessment of rheumatoid arthritis activity. Arthritis Rheum. 1995;38:38–43
  35. Lee P, Baxter A, Dick WC, Webb J. Assessment of grip strength measurement in rheumatoid arthritis. Scand J Rheumatol. 1973;3:17–23
  36. Pincus T, Callahan LF. Rheumatology function tests: grip strength, walking time, button test and questionnaires document and predict long-term morbidity and mortality in rheumatoid arthritis. J Rheumatol. 1992;19:1051–1057
  37. Deohar SD, Dick WC, Hodgkinson R, Buchanan WW. Measurement of clinical response to anti-inflammatory drug therapy in rheumatoid arthritis. Q J Med. 1973;42:387–401
  38. Pincus T, Callahan LF, Brooks RH. Quantitative nonlaboratory measures to monitor and predict the course of rheumatoid arthritis. In:  Ehrlich GE editors. Rehabilitation Management of Rheumatic Conditions. Baltimore (MD): Williams and Wilkins; 1986;p. 45–64
  39. Smith TW, Christensen AJ. Positive and negative affect in rheumatoid arthritis: increased specificity in the assessment of emotional adjustment. Ann Behav Med. 1996;18:75–78
  40. Smith TW, Peck JR, Ward JR. Helplessness and depression in rheumatoid arthritis. Health Psychol. 1990;9:377–389
  41. Smith TW, Christiansen AJ, Peck JR, Ward JR. Cognitive distortion, helplessness, and depressed mood in rheumatoid arthritis: a four-year longitudinal analysis. Health Psychol. 1994;13:213–217
  42. Ware JE, Johnston SA, Davies-Avery A, Brook RH. Conceptualization and measurement of health for adults in the Health Insurance Study. Mental Health. Santa Monica (CA): RAND Corp; 1979;
  43. Ware JE, Manning WG, Duan N, Wells KB, Newhouse JP. Health Status and the use of outpatient mental health services. Am Psychol. 1984;39:1090–1100
  44. Veit CT, Ware JE. The structure of psychological distress and well-being in general populations. J Consult Clin Psychol. 1983;51:730–742
  45. Hays RD, Stewart AL. The structure of self-reported health in chronic disease patients. J Consult Clin Psychol. 1990;2:22–30
  46. Cohen J. Statistical Power Analyses for the Behavioral Sciences. 2nd ed.. Hillsdale (NJ): Laurence Erlbaum Associates; 1988;
  47. Pradhan EK, Baumgarten M, Langenberg P, Handwerger B, Kaplan Giplin A, Magyari T, et al. Effect of mindfulness-based stress reduction in rheumatoid arthritis patients. Arthritis Care Res. 2007;57:1134–1142
  48. Taal E, Riemsma RP, Herman LMB, Seydel ER, Rasker JJ, Wiegman O. Group education for patients with rheumatoid arthritis. Patient Ed Counsel. 1993;20:177–187
  49. Lorig K, Lubeck D, Kraines RG, Seleznick M, Holman HR. Outcome of self-help education for patients with arthritis. Arthritis Rheum. 1985;28:680–685
  50. Lorig KR, Mazonson PD, Holman HR. Evidence suggesting that health education for self-management in patients with chronic arthritis has sustained health benefits while reducing health care costs. Arthritis Rheum. 1993;36:439–446
  51. Lorig K, Holman H. Arthritis self-management studies: a twelve-year review. Health Educat Quat. 1993;20:17–28
  52. Goeppinger J, Arthur MW, Baglioni AJ, Brunk SE, Brunner CM. A reexamination of the effectiveness of self-care education for patients with rheumatoid arthritis. Arthritis Rheum. 1989;32:706–716
  53. Scholten C, Brodowicz T, Graninger W, Gardavsky I, Pils K, Pesau B, et al. Persistent functional and social benefit 5 years after a multidisciplinary arthritis training program. Arch Phys Med Rehabil. 1999;80:1282–1287
  54. Maisiak R, Austin JS, West SG, Heck L. The effect of person-centered counseling on the psychological status of persons with systemic lupus erythematosus or rheumatoid arthritis (A randomized, controlled trial). Arthritis Care Res. 1996;9:60–66
  55. Radojevic V, Nicassio PM, Weisman MH. Behavioral intervention with and without family support for rheumatoid arthritis. Behav Ther. 1992;23:13–30
  56. Leibing E, Pfingsten M, Bartmann U, Rueger U, Chuessler G. Cognitive-behavioral treatment in unselected rheumatoid arthritis patients. Clin J Pain. 1999;15:58–66
  57. Evers AWM, Kraaimaat FW, van Riel PLCM, de Jong AJL. Tailored cognitive-behavioral therapy in early rheumatoid arthritis for patients at risk: a randomized controlled trial. Pain. 2002;100:141–153
  58. Sharpe L, Sensky T, Timberlake N, Ryan B, Allard S. Long-term efficacy of a cognitive behavioural treatment from a randomized controlled trial for patients recently diagnosed with rheumatoid arthritis. Rheumatology. 2003;42:435–441
  59. O'Leary A, Shoor S, Lorig K, Holman HR. A cognitive-behavioral treatment for rheumatoid arthritis. Health Psychol. 1988;7:527–544
  60. Lindroth Y, Brattström M, Bellman I, Ekestaf Y, Olofsson Y, Strömbeck B, et al. A problem-based education program for patients with rheumatoid arthritis: evaluation after three and twelve months. Arthritis Care Res. 1997;10:325–332
  61. Parker JC, Smarr KL, Buckelew SP, Stucky-Ropp RC, Hewett JE, Johnson JC, et al. Effects of stress management of clinical outcomes in rheumatoid arthritis. Arthritis Rheum. 1995;38:1807–1818

 This work was supported by research grant R01 AR 4701401 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases. This study has been registered with ClinicalTrials.gov and received the identifier NCT00056667.

PII: S0049-0172(10)00052-1

doi: 10.1016/j.semarthrit.2010.04.001

Seminars in Arthritis and Rheumatism
Volume 40, Issue 3 , Pages 222-232 , December 2010

Article Tools

* Image Usage & Resolution