Seminars in Arthritis and Rheumatism
Volume 40, Issue 4 , Pages 307-313, February 2011

Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid and Their Relation to Response to Therapy of Childhood-Onset Systemic Lupus Erythematosus

  • Anna Carmela P. Sagcal-Gironella, MD, MS

      Affiliations

    • Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
  • ,
  • Tsuyoshi Fukuda, PhD

      Affiliations

    • Division of Clinical Pharmacology and Pediatric Pharmacology Research Unit (PPRU), Cincinnati Children's Hospital Medical Center, Cincinnati, OH
    • Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH
  • ,
  • Kristina Wiers, MD, MS

      Affiliations

    • Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
  • ,
  • Shareen Cox, BS

      Affiliations

    • Division of Clinical Pharmacology and Pediatric Pharmacology Research Unit (PPRU), Cincinnati Children's Hospital Medical Center, Cincinnati, OH
  • ,
  • Shannen Nelson, MSN, RN

      Affiliations

    • Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
  • ,
  • Blair Dina, BS

      Affiliations

    • Division of Rheumatology, Children's Memorial Hospital, Chicago, IL
  • ,
  • Catherine M.T. Sherwin, PhD, BSc(Hons)

      Affiliations

    • Division of Clinical Pharmacology and Pediatric Pharmacology Research Unit (PPRU), Cincinnati Children's Hospital Medical Center, Cincinnati, OH
  • ,
  • Marisa S. Klein-Gitelman, MD, MPH

      Affiliations

    • Division of Rheumatology, Children's Memorial Hospital, Chicago, IL
  • ,
  • Alexander A. Vinks, PharmD, PhD

      Affiliations

    • Division of Clinical Pharmacology and Pediatric Pharmacology Research Unit (PPRU), Cincinnati Children's Hospital Medical Center, Cincinnati, OH
    • Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH
  • ,
  • Hermine I. Brunner, MD, MSc

      Affiliations

    • Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
    • Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH
    • Corresponding Author InformationAddress reprint requests to: Hermine I. Brunner, MD, MSc, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 4010, Cincinnati, OH 45229-3039

published online 23 July 2010.

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 The study is supported by a NIAMS P60-AR047884 grant, the CCHMC Translational Research Initiative, and the Center for Clinical and Translational Research UL1-RR026314. Drs. Vinks and Fukuda are supported by NIH Grant 5U10HD037249. Dr. Vinks is supported by NIH Grant 5K24HD050387. Drs. Wiers and Sherwin are supported by a NIAMS T32 AR007594 grant. Dr. Wiers is supported by the NIH Loan Repayment Program.

PII: S0049-0172(10)00082-X

doi:10.1016/j.semarthrit.2010.05.007

Seminars in Arthritis and Rheumatism
Volume 40, Issue 4 , Pages 307-313, February 2011