Treatment of pain due to fibromyalgia with topical capsaicin: A pilot study
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Nutraceuticals: A source of benefaction for neuropathic pain and fibromyalgia
2022, Journal of Functional FoodsCitation Excerpt :In addition, capsaicin cream (0.025% and 0.075%) was used to treat pain associated with primary fibromyalgia. Patients treated with capsaicin cream experienced less tenderness, minimal pain, and improved mood (depression, anxiety) due to lower levels of substance P and NK1-receptor blockade, which are responsible for the anti-anxiety effect (Casanueva et al., 2013; McCarty et al., 1994). Capsaicin also inhibits the synthesis of proinflammatory mediators (IL-1β, IL-6, TNF-α), which aggravate hyperalgesia, allodynia, and depression (Wallace et al., 2001).
Mineral, Vitamin, and Herbal Supplements
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2008, Complementary Therapies for Physical TherapyOverview of Biologically Based Therapies in Rehabilitation
2007, Complementary Therapies for Physical Therapy: A Clinical Decision-Making ApproachThe Fibromyalgia Syndrome
2006, Decision Making in Pain ManagementNutraceuticals for fibromyalgia and neuropathic pain
2023, Exploring Complementary and Alternative Medicinal Products in Disease Therapy
Supported by GenDerm Corporation, Lincolnshire, IL, and Knoll Pharmaceutical Company, Whippany, NJ.
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Dana Trotter, MD, is currently a Clinical Rheumatologist, Kenosha, WI.
Copyright © 1994 W.B. Saunders Company. Published by Elsevier Inc. All rights reserved.