« Previous
Next »
Seminars in Arthritis and Rheumatism
Volume 26, Issue 5
, Pages 724-739
, April 1997
Antiphospholipid antibodies: Basic immunology and assays
References
- (chap 12) . Introduction to biological membranes. In: Biochemistry. 3rd ed.. New York: WH Freeman & Company; 1988;p. 283–312
- . Immunochemical studies of phospholipids. VI. Haptenic activity of phosphatidylinositol and the role of lecithin as an auxiliary lipid. J Immunol. 1970;105:502–511
- . The immunological relations between acid phospholipids and their antibodies. Jpn J Exp Med. 1971;41:31–38
- Affinity purified anti-cardiolipin and anti-DNA antibodies. J Clin Lab Immunol. 1985;17:155–162
- Cross reactivity of antiphospholipid antibodies. J Clin Lab Immunol. 1985;16:1–6
- . Anti-phospholipid antibodies. Clin Rheum Dis. 1985;11:591–609
- Anticardiolipin antibodies: isotype distribution and phospholipid specificity. Ann Rheum Dis. 1987;46:1–6
- Antibodies to phosphatidylethanolamine in antiphospholipid syndrome and systemic lupus erythematosus: their correlation with anticardiolipin antibodies and β2-glycoprotein I plasma levels. Autoimmunity. 1993;16:245–249
- . Haemolytic anemia related to an IgM autoantibody to phosphatidylcholine that binds in vitro to stored and to bromelin-treated human erythrocytes. J Autoimmunol. 1990;3:773–787
- . New diagnostic strategies for lupus anticoagulants and antiphospholipid antibodies. Haemostasis. 1994;24:155–164
- . Eine serodiagnostische reaktion bei syphilis. Dtsch Med Wochenschr. 1906;32:745–746
- . A simplified preparation of cardiolipin, with a note on purification of lecithin for serologic use. J Biol Chem. 1945;161:71–82
- . Universal serologic reaction with lipid antigen. III. In syphilis. Am J Clin Pathol. 1949;19:401–407
- . Biologic false positive reaction for syphilis. N Engl J Med. 1963;268:402–405
- . Immunology and clinical importance of antiphospholipid antibodies. Adv Immunol. 1991;49:193–259
- . Biologically false positive serologic tests for syphilis. JAMA. 1952;150:467–473
- . The natural history of systemic lupus erythematosus: an approach to its study through chronic biologic false positive reactors. J Chronic Dis. 1955;1:297–316
- . Systemic lupus erythematosus preceded by false positive test for syphilis: presentation of five cases. Ann Intern Med. 1951;37:559–565
- . Connective tissue disease and the chronic biologic false positive test for syphilis. Med Clin North Am. 1966;50:1271–1279
- Antiphospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: β2-glycoprotein I (apolipoprotein H). In: Proc Natl Acad Sci USA. 87:1990;p. 4120–4124
- Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor. Lancet. 1990;335:1544–1547
- Anticardiolipin cofactor(s) and differential diagnosis of autoimmune disease. Lancet. 1990;336:177–178
- Heterogeneity of anticardiolipin antibodies defined by the anticardiolipin cofactor. J Immunol. 1992;148:3885–3891
- A phospholipid β2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection. Lupus. 1992;1:75–81
- In: Asherson RA, Cervera R, Piette J-C, Shoenfeld Y editor. The Antiphospholipid Syndrome. Boca Raton, FL: CRC Press; 1996;p. 3–12In: Asherson RA, Cervera R, Piette J-C, Shoenfeld Y editor. The Antiphospholipid Syndrome. Boca Raton, FL: CRC Press; 1996;p. 29–48(Chapt 3)
- . The antiphospholipid syndrome. J R Coll Phys Lond. 1994;28:301–304
- . Experimental models for antiphospholipid studies. Haemostasis. 1994;24:204–207
- Vasculitis associated with antiphospholipid syndrome. Semin Arthritis Rheum. 1995;24:273–281
- . Clincopathologic correlations of the antiphospholipid syndrome. Semin Arthritis Rheum. 1995;24:262–272
- . Mechanisms of action of antiphospholipid antibodies in the antiphospholipid syndrome. Int Arch Allergy Immunol. 1995;106:8–12
- . Pathology and pathogenesis of vascular injury in systemic lupus erythematosus: interactions of inflammatory cells and activated endothelium. Arthritis Rheum. 1996;39:9–22
- . Über ein bisher unbekanntes niedermoleculares β2-globulin des Human Serums. Naturwissenschaften. 1961;48:719
- Complete nucleotide and deduced amino acid sequence of human β2-glycoprotein I. Biochem J. 1991;277:387–391
- Characterization of isoelectric subspecies of asialo-β2-glycoprotein I. Biochem J. 1989;260:531–554
- . Complete amino acid sequence of human plasma β2-glycoprotein I. In: Proc Natl Acad Sci USA. 81:1984;p. 3640–3644
- . Structure-function relationships of the complement components. Immunol Today. 1989;10:177–180
- . Binding of β2-glycoprotein I to platelets: effect of adenylate cyclase activity. Thromb Res. 1980;19:225–237
- . Purification, characterization and identification of an agglutinin in human serum. Biochim Biophys Acta. 1979;579:396–408
- . β2-glycoprotein I (apolipoprotein H) interactions with phospholipid vesicles. Int J Biochem. 1984;16:511–515
- DNA-binding proteins in Yoshida ascites tumor fluid. Biochem Biophys Acta. 1976;434:490–501
- . Investigations on β2-glycoprotein I in the rat: isolation from serum and demonstration in lipoprotein density fractions. Int J Biochem. 1980;11:265–270
- . The binding of β2-glycoprotein I to human serum lipoproteins: distribution among density fractions. FEBS Lett. 1979;102:183–186
- . β2-glycoprotein I: a plasma inhibitor of the contact activation of the intrinsic blood coagulation pathway. Blood. 1985;66:1086–1091
- Prothrombinase activity of human platelets is inhibited by β2-glycoprotein I. Biochim Biophys Acta. 1986;884:142–149
- . β2-glycoprotein I (apo-H) inhibits the release reaction of human. platelets during ADP-induced aggregation. Atherosclerosis. 1987;63:109–114
- Induction of antiphospholipid autoantibodies by immunization with β2-glycoprotein I (apolipoprotem H). J Clin Invest. 1992;90:1105–1109
- Immunization of a rabbit with β2-glycoprotein I induces charge-dependent crossreactive antibodies that bind anionic phospholipids and have similar reactivity as autoimmune anti-phospholipid antibodies. J Immunol. 1995;155:958–966
- . Induction of phospholipid-binding antibodies in mice and rabbits by immunization with human β2-glycoprotein I or anti-cardiolipin antibodies alone. Clin Exp Immunol. 1993;93:269–272
- . Anti-β2-glycoprotein I antibodies: detection and association with thrombosis. Br J Haematol. 1995;89:397–402
- Activity, disulphide mapping and structural modelling of the fifth domain of human β2-glycoprotein I. FEBS Lett. 1992;313:193–197
- . Identification of a region of β2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activity. In: Proc Natl Acad Sci USA. 90:1993;p. 2141–2145
- . The fifth domain of β2-glycoprotein I contains a phospholipid binding site (Cys281-Cys288) and a region recognized by anticardiolipin antibodies. J Immunol. 1994;152:653–659
- Epitope specificity of monoclonal anti-β2-glycoprotein I antibodies derived from patients with the anti-phospholipid syndrome. J Immunol. 1995;155:1629–1636
- Measurement of anti-phospholipid antibodies by ELISA using β2-glycoprotein I as an antigen. J Immunol Methods. 1991;143:223–229
- . Association of anti-β2-glycoprotein I antibodies with lupus-type circulating anticoagulant and thrombosis in systemic lupus erythematosus. Am J Med. 1992;93:181–186
- Some antiphospholipid antibodies bind to beta 2-glycoprotein I in the absence of phospholipid. Br J Haematol. 1992;82:571–574
- Anticardiolipin antibodies recognize β2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface. J Exp Med. 1994;179:457–462
- . Surface modification of polystyrene by γ-irradiation. Appl Spectrosc. 1990;44:808–814
- Anticardiolipin autoantibodies recognize β2-glycoprotein I in the absence of phospholipid. J Immunol. 1995;154:954–960
- . Changes in β2-glycoprotein I antigenicity induced by phospholipid binding. Thromb Haemostasis. 1993;69:361–365
- . Multiple interactive residues of recognition: elucidation of discontinuous epitopes with linear peptides. J Immunol. 1996;157:183–188
- Monoclonal antibodies from NZW X BXSB F1 mice to β2-glycoprotein I and cardiolipin: species specificity and charge-dependent binding. J Immunol. 1996;156:2631–2641
- . (NZW X BXSB) Fl hybrid: a model of acute lupus and coronary disease with myocardial infarction. J Exp Med. 1996;154:216–221
- Anticardiolipin antibodies in NZW X BXSB Fl mice: a model of anti-phospholipid syndrome. J Immunol. 1992;149:1063–1068
- . Acquired inhibitors of blood coagulation. Prog Hemostas Thromb. 1972;1:75–95
- . A hemorrhagic disorder caused by circulating anticoagulant in patients with disseminated lupus erythematosus. J Lab Clin Invest. 1952;13:621–622
- . Hypergammaglobulinemia, circulating anticoagulant, and biological false positive Wassermann reaction: a study of two cases. J Lab Clin Med. 1957;49:694–707
- . Lupus anticoagulants: characteristics, methods of laboratory detection and some clinical associations. In: Harris EN, Exner T, Hughes GRV, Asherson RA editor. Phospholipid binding antibodies. Boca Ratan, FL: CRC; 1991;p. 141–158
- . Monoclonal immunoglobulin Mλ coagulation inhibitor with phospholipid specificity: mechanism of a lupus anticoagulant. J Clin Invest. 1980;66:397–405
- Inhibition of phospholipid and platelet-dependent prothrombinase activity in the plasma of patients with lupus anticoagulants. Br J Haematol. 1989;72:549–555
- . Purification and kinetic studies of a circulating anticoagulant in a suspected case of lupus erythematosus. Thromb Haemorrh. 1985;14:88–115
- Immunological specificity and mechanism of action of IgG lupus anticoagulants. Blood. 1996;70:69–76
- Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon β2-glycoprotein I. J Clin Invest. 1992;90:1100–1104
- . Separation of anticardiolipin antibodies from lupus anticoagulant on a phospholipid-coated polystyrene column. Biochem Biophys Res Commun. 1988;155:1001–1007
- . Anticardiolipin antibodies and lupus anticoagulants comprise antibody subgroups with different phospholipid binding characteristics. Br J Haematol. 1989;73:506–513
- Lupus anticoagulant activity is frequently dependent on the presence of β2-glycoprotein I. Thromb Haemost. 1992;67:499–502
- Anticoagulant activity of β2-glycoprotein I is potentiated by a distinct subgroup of anticardiolipin antibodies. Thromb Haemost. 1992;68:297–300
- β2-glycoprotein I-dependent and independent binding of anticardiolipin antibodies in patients with recurrent spontaneous abortions. J Clin Lab Anal. 1994;8:255–259
- . Acquired circulating anticoagulants in systemic collagen disease autoimmune thromboplastin deficiency. Blood. 1955;10:691–706
- . Prothrombin as co-factor in the circulating anticoagulant in systemic lupus erythematosus?. Thromb Diath Haemorrh. 1959;3:237–256
- A mechanism for the hypoprothrombinemia of the acquired hypoprothrombineia-lupus anticoagulant syndrome. Blood. 1983;61:684–692
- Acquired hypoprothrombinernia due to nonneutralizing antibodies to prothrombin: mechanism and management. Blood. 1985;65:1538–1543
- . Abnormal prothrombin crossed-immunoelectrophoresis in patients with lupus inhibitors. Blood. 1984;64:807–816
- . Antiprothrombin antibodies and the lupus anticoagulant. Blood. 1988;72:512–519
- Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin. Thromb Haemost. 1991;66:629–632
- Chap 2 . The blood coagulation factors: their cDNAs, genes, and expression. In: Colman RW, Hirsh J, Marder VJ, Salzman EW editor. Hemostasis and Thrombosis: Basic Principles and Clinical Practice. 3rd ed. Philadelphia: Lippincott; 1994;p. 19–54
- Chap 13 . Biochemistry and physiology of protein C, protein S, and thrombomodulin. In: Colman RW, Hirsh J, Marder VJ, et al. editor. Hemostasis and thrombosis: basic principles and clinical practice. ed 3. Philadelphia: Lippincott; 1994;p. 259–276
- Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: an explanation for theirpathogenic mechanism?. Blood. 1993;81:2618–2625
- [abstract] Human thrombomodulin is inhibited by IgG from two patients with nonspecific anticoagulants. Blood. 1983;62:299a
- . Lupus-like anticoagulants, modulation of the protein C pathway and thrombosis. Thromb Haemost. 1987;58:679–681
- Effect of lupus anticoagulant on antithrombogenic properties of endothelial cells: inhibition of thrombomodulin-dependent protein C activation. Thromb Haemost. 1988;60:54–58
- . Impaired catalytic function of activated protein C: a new in vitro manifestation of lupus anticoagulant. Blood. 1989;74:2426–2432
- Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies. Br J Haematol. 1990;76:101–107
- . Antiphospholipid antibodies: specificity and pathophysiology. Baillieres Clin Haematol. 1993;6:691–709
- Some antiphospholipid antibodies inhibit phospholipase A2 activity. J Lab Clin Med. 1992;120:67–77
- Antiphospholipid antibodies: a critique of their heterogeneity and hegemony. Semin Thromb Hemost. 1994;20:89–100
- . Antiphospholipid antibodies and disease. Br J Rheumatol. 1995;34:1009–1030
- IgG subclass and light chain distribution of anticardiolipin and anti-DNA antibodies in systemic lupus erythematosus. Ann Rheum Dis. 1988;47:286–290
- IgG subclass distribution of anticardiolipin antibody in patients with systemic lupus erythematosus. J Rheumatol. 1988;15:1764–1767
- Subclasses of IgG anticardiolipin antibodies in patients with systemic lupus erythematosus. Scand J Immunol. 1991;34:265–271
- . Is the antiphospholipid syndrome caused by antibodies directed against physiologically relevant phospholipid-protein complexex?. J Lab Clin Med. 1992;120:10–12
- . The structural specificity of antiphospholipid antibodies in autoimmune disease. Chem Phys Lipids. 1986;40:315–332
- . Immobilization of Treponema pallidum in vitro by antibody produced in syphilis infection. J Exp Med. 1949;89:369–393
- . A disorder of blood coagulation in systemic lupus erythematosus. J Clin Invest. 1955;34:1814–1822
- . Acquired inhibitors in nonhemophilic patients. Haemostasis. 1974;3:65–93
- . Disorders of hemostatic function in patients with systemic lupus erythematosus. Semin Arthritis Rheum. 1975;4:241–252
- A clinical study of the lupus anticoagulant. Blood. 1976;48:499–509
- Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancet. 1983;2:1211–1214
- . Antiphospholipid antibodies in syphilis and a thrombotic subset of SLE: distinct profiles of epitope specificity. Clin Exp Immunol. 1985;59:449–456
- Antiphospholipid antibodies and biological false positive serological test for syphilis in patients with systemic lupus erythematosus. Clin Exp Immunol. 1984;56:193–199
- Use of an enzyme-linked immunosorbent assay and of inhibition studies to distinguish between antibodies to cardiolipin from patients with syphilis or autoimmune disorders. J Infect Dis. 1988;157:23–31
- The primary antiphospholipid syndrome: major clinical and serological features. Medicine. 1989;68:366–374
- . Enzyme linked immunosorbent assay for detection of antibodies to the veneral disease research laboratory (VDRL) antigen in syphilis. J Clin Microbiol. 1987;25:1711–1716
- . Serological detection of antiphospholipid antibodies. Stroke. 1992;23:I
- . Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbent assay (ELISA): standardization and quantitation of results. Clin Exp Immunol. 1985;62:738–745
- Detection of antiphospholipid antibodies by flow cytometry: rapid detection of antibody isotype and phospholipid specificity. Thromb Haemost. 1993;70:603–607
- Detection of bilayer phospholipid-binding antibodies using flow cytometry. Clin Exp Immunol. 1996;103:171–175
- . Anticardioiipin antibodies and thrombosis. Hematol Oncol Clin North Am. 1992;6:1287–1299
- Antiphospholipid antibodies and thrombosis in systemic lupus erythematosus: Comparison of three lupus anticoagulant assays and anticardiolipin ELISA in 188 patients. Blood Coagul Fibrinolysis. 1992;3:407–414
- . Antiphospholipid antibody syndrome. JAMA. 1992;268:1451–1453
- . Coagulation assays for the lupus anticoagulant: review and critique of current methodology. Stroke. 1992;23(Suppl 1):I
- . Distinguishing plasma lupus anticoagulants from anti-factor antibodies using hexagonal (II) phase phospholipids. Thromb Haemost. 1989;62:892–896
PII: S0049-0172(97)80041-8
© 1997 Published by Elsevier Inc.
« Previous
Next »
Seminars in Arthritis and Rheumatism
Volume 26, Issue 5
, Pages 724-739
, April 1997
